Familial aggregation of stroke. The Framingham Study.
نویسندگان
چکیده
منابع مشابه
Familial aggregation of stroke. The Framingham Study.
BACKGROUND AND PURPOSE Family history is perceived to be an important risk factor for stroke despite conflicting published data. We examined patterns of familial aggregation of stroke among three generations using data from the Framingham Study. METHODS Cox proportional hazards analyses, adjusting for known stroke risk factors, were used to examine familial concordance in three groups: (1) me...
متن کاملFamilial Aggregation of Stroke
Stroke is the second leading cause of death worldwide, and the leading cause of acquired disability in adults in most regions. Fifteen million people worldwide suffer a stroke each year with devastating effects; one third of these individuals die and another one third remains permanently disabled. However, there is a considerable additional unreported asymptomatic cerebrovascular disease. Accor...
متن کاملFamilial aggregation of left ventricular geometry and association with parental heart failure: the Framingham Heart Study.
BACKGROUND Data regarding the familial aggregation of left ventricular (LV) geometry and its relations to parental heart failure (HF) are limited. METHODS AND RESULTS We evaluated concordance of LV geometry within 1093 nuclear families in 5758 participants of the original (parents) (n=2351) and offspring (n=3407) cohorts of the Framingham Heart Study undergoing routine echocardiography in mid...
متن کاملFamilial aggregation of ischemic stroke in young women: the Stroke Prevention in Young Women Study.
BACKGROUND AND PURPOSE Stroke occurs infrequently in young adults. While a familial basis for older onset stroke is well established, the extent of familial clustering in young-onset stroke is unknown. To address this issue, we compared the frequency of stroke in relatives of stroke cases to that in relatives of controls across different ages and by stroke subtype. METHODS Through a populatio...
متن کاملDementia after stroke: the Framingham Study.
BACKGROUND AND PURPOSE Identification of risk factors for dementia after stroke is best performed in comparison with stroke-free controls, because older subjects at high risk for stroke also have a substantial risk of dementia in the absence of stroke. Previous case-control studies were hospital-based. We used a nested case-control design to prospectively evaluate these risk factors in the comm...
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ژورنال
عنوان ژورنال: Stroke
سال: 1993
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.24.9.1366